One system.
Multiple mechanisms of action.
All the Frequencies You Need to Deliver Relief
Uniquely offering 2-1200 and 10,000 Hz stimulation, enabling multiple mechanisms of action. Senza® systems offer both direct neural inhibition with 10 kHz Therapy and dorsal column stimulation with lower frequencies. These mechanisms can be used simultaneously or independently to help manage chronic pain.
How 10 kHz Therapy Works
Rather than stimulating the dorsal column, 10 kHz Therapy directly targets inhibitory neurons in the dorsal horn, providing pain relief without paresthesia.1,2
Frequency Matters
Frequencies above 5,000 Hz have a unique inhibitory effect on pain circuitry in the dorsal horn. The stimulation drives inhibitory neurons without meaningfully activating the excitatory neurons. This selective activation, called “direct neural inhibition,” reduces the hyperactivity of wide dynamic range neurons implicated in chronic pain.
Frequency is Positively Correlated with Pain Relief
In the first frequency titration study in humans, patients were given a range of frequencies to compare clinical outcomes. Only 5,882 Hz demonstrated improved pain relief versus sham. Additional studies on 10 kHz Therapy validate the importance of frequency.
Maximum Versatility with Both Mechanisms of Action
Offering physicians the ability to treat patients with direct neural inhibition and dorsal column stimulation. Waveforms can be paired or delivered independently so you can provide your patients the broadest range of solutions.
